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CT引导下经皮肺穿刺活检术对于肺癌的诊断价值

The Diagnostic Value of CT-guided Percutaneous Pulmonary Biopsy for Lung Cancer

作者: 专业:外科学 导师:田大力 年度:2010 学位:硕士  院校: 中国医科大学

Keywords

CT-guided, lung cancer, pulmonary biopsy

        目的探讨CT引导下经皮肺穿刺活检术对于肺癌的诊断价值。临床资料及方法回顾性分析我院78例患者,在西门子多排螺旋CT机引导下,采用美国巴德公司的MN1816软组织活检针(18G),C1816B同轴活检针(17G)及Magnum活检枪,进行经皮肺穿刺活检术。根据穿刺病理结果将研究对象分为恶性组、良性组及未诊断组,并对结果进行统计学分析。结果78例经皮肺穿刺活检术均穿刺成功,穿刺成功率为100%,其中恶性肿瘤48例,良性肿瘤20例,由于组织少或技术原因未诊断10例。敏感度、特异度、准确率分别为83%、100%、87%。通过统计学分析发现病变最大直径(以3cm,5cm为界),P>0.05,没有统计学意义;病变距胸壁距离(以5cm为界),P<0.05,有统计学意义。结论1.CT引导下经皮肺穿刺活检术对于肺癌的诊断具有重要的临床价值;2.本研究CT引导下经皮肺穿刺活检术对肺癌的诊断具有较高的敏感度,特异度及准确率,分别为:83%、100%、87%;3.CT引导下经皮肺穿刺活检术具有安全性高,创伤性小,并发症少等优点。
    ObjectiveThe aim of this study was to explore the diagnosis value of lung cancer by using CT-guided percutaneous pulmonary biopsy.Materials and MethodsRetrospective analysis the 78 patients underwent CT-guided percutaneous pulmonary biopsy with the coaxial tissue biopsy needle and core tissue biopsy needle in our hospitial from 2008 Jan to 2009 Oct. And evaluated the factors influencing accuracy of CT-guided percutaneous pulmonary biopsy.ResultsAll of the pulmonary biopsy were successful. Out of a total of 78 biopsies,48 were positive for malignancy,and 20 were benign,the other 10 were non-diagnostic. The sensitivity, specificity and accuracy for the diagnosis of malignancy were 83%,100%,87%.We found no statistical significant different in the lesion size(X2= 1.850, P=0.397),but the diatance of the lesion to the chest wall had the statistical significant(X2=3.891, P=0.049).ConclusionsIt was important to diagnose lung cancer by using percutaneous pulmonary biopsy with CT-guided, especially for the peripheral lung cancer.The sensibility, specificity and accuracy were satisfactory. Moreover, it was very safe, minimally invasive and there were only a few complications. CT-guided percutaneous pulmonary biopsy had an important clinical significance for the diagnosis of lung cancer,particularly those with peripheral pulmonary lung cancer.
        

CT引导下经皮肺穿刺活检术对于肺癌的诊断价值

一、摘要4-8
    1. 中文结构式摘要4-6
    2. 英文结构式摘要6-7
二、英文缩略词8-9
三、论文9-21
    1. 前言9
    2. 临床资料及方法9-11
    3. 结果11-14
    4. 讨论14-17
    5. 结论17-18
    6. 本研究创新性的自我评价18-19
    7. 参考文献19-21
四、附录21-31
    1. 综述21-29
    2. 在学期间科研成绩29-30
    3. 致谢30-31
    4. 个人简介31
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